Human Microglial Cells in the Mouse Brain 4

Human Microglial Cells in the Mouse Brain 4

Marine Krzisch

Whitehead Institute

Microglia is a brain cell capable of organizing a potent inflammatory response. This picture shows different human microglial cells in the mouse brain, 2 months after injection, after we injected the mice with a molecule causing inflammation in the brain. We took this picture to evaluate how differently Parkinson and control microglia responded to an inflammatory challenge, by looking at their morphology. We are studying the effects of a familial Parkinson’s disease mutation on human microglia grown into the mouse brain, in presence or absence of inflammatory challenge. 

four branching neurons side by side in red, green, yellow, and cyan

More like this