Neuronal Network Nebula

Neuronal Network Nebula

Byunguk Kang, Serwah Danquah, Michael Murphy, Nhan Huynh, Samouil L. Farhi, Ernest Fraenkel

Broad Institute, MIT Department of Biological Engineering

Genetic screens can help researchers characterize the functions and roles of many genes that are likely to affect a disease progression or therapeutic outcome. This image shows a pool of genetically modified neurons (a nerve cell) derived from human stem cells. A unique set of three colors from 7 channels (Red, Orange, Yellow, Green, Blue, Indigo, Violet) represents different barcodes for identifying genetic background, resulting in a visual appearance of 20 different colors. This approach enables researchers to identify which genes were knocked down in each cell and study their effect on cellular health and neuronal morphology.  

glowing orange neurons form a pale feathery string-like web against a black background

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