Isolating Proteins to Help Grow Stem Cells

Isolating Proteins to Help Grow Stem Cells

George Eng, Omer Yilmaz

Koch Institute at MIT, MIT Department of Biology

This image is a reporter cell line that shows activity when exposed to new proteins purified in the our lab that grow stem cells.

We took this image because I use the red color as a direct readout (reporter) of Wnt protein function, which is a set of proteins we use to grow mouse and human organoids or mini intestines in the lab. We were trying to learn how to isolate the Wnt proteins so that they can remain functional and support stem cell growth.

This is part of our ongoing search to find ways to grow intestinal stem cells.


clusters of red and blue cells glow against a black background

More like this