Reach to Teach: A lesson on d*raining vaccines
Reach to Teach: A lesson on d*raining vaccines
Archana V Boopathy, Sudha Kumari, Paula T Hammond and Darrell J Irvine
Koch Institute at MIT, MIT Department of Chemical Engineering, MIT Department of Biological Engineering, MIT Department of Materials Science and Engineering
Vaccine targeting to the lymph node, an immune cell rich organ, is critical for vaccine efficacy. The images was taken 7 days after a preventive HIV vaccine was administered to mice through a dermal nanoparticle delivery device and shows vaccine accumulation in the lymph node. The vaccine that has reached the lymph node would interact with (teach) the immune cells to produce strong vaccine specific immune responses necessary to prevent a future infection taking us one step closer to a world without HIV.