Spaces Between: Engineering Protection for Cell Therapies 3

Spaces Between: Engineering Protection for Cell Therapies 3

Benjamin N. Muller, Taksim Ahmed, Keith Smith, Giovanni Traverso

MIT Department of Mechanical Engineering

This image zooms into clusters of living cells embedded within a hydrogel matrix, exposing their dense packing and the void spaces that shape how molecules move between them. Mapping this microscopic architecture is essential for determining how efficiently drugs travel through the network and are taken up by cells. This research advances engineered delivery platforms designed to protect fragile cell clusters from the damaging mechanical stresses of administration. By preserving cell viability during delivery, these systems help ensure cell-based therapies can survive long enough to function once inside the body.

Close-up of a green surface showing visible cracks and texture variations.

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