This image shows immune cells, like neutrophils and T cells, in action as they respond to an ear punch in mouse skin two days post-injury. Different immune cells are required for both a productive anti-microbial response and formation of the new tissue, and we are interested in understanding the dynamic and carefully timed coordination required for successful healing. 

Cutaneous wound healing is a sequential, highly regulated process that is essential for tissue regeneration and pathogen clearance. While the overall timeline of wound repair is well-documented, the detailed spatiotemporal dynamics of immune cell populations and the mechanisms coordinating the transition between healing stages remain poorly understood. Our research aims to gain deeper insights into how the immune system orchestrates these opposing functions during wound healing, with a particular focus on neutrophils and regulatory T cells (Tregs).