Heart of (Stained) Glass
Heart of (Stained) Glass
Huaiyao Peng
Koch Institute at MIT
These are pig fallopian tube organoids, which are like miniature versions of fallopian tube tissues. They have a distinctive appearance because they carry specific p53 mutations. These mutations make the organoids behave similarly to serous tubal intraepithelial carcinoma (STIC), which is an early-stage condition that can develop into high-grade serous ovarian cancer (HGSOC).
This image showcases a breakthrough organoid model that mimics STIC lesions, providing a unique opportunity to study and potentially improve early detection and treatment strategies for high-grade serous ovarian cancer.
