Selective Photoconversion of Cells

Selective Photoconversion of Cells

Anthony Tabet and Luciano Santollani

Every cell in this mouse is green, but if you shine UV light at it, cells from these mice turn red. We can use this special property to track how cells, especially immune cells, migrate from one part of the body to another. In this sample, you see a colon sample from this mouse that was partially photo-converted to red.

We are interested in looking at how immune cells travel to and from the gut when there are multiple tumors in a mouse and only one is treated with immunotherapy. This allows us to explore how well our potential therapies are at treating distal, metastatic tumors.  

hook-like fluorescent green tube with red fluorescence at the curve

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