Mathematical Model of Tumor Targeting

Mathematical Model of Tumor Targeting

Submitted by Professor Dane Wittrup of the Koch Institute 

MIT Department of Biological Engineering, Koch Institute at MIT, MIT Department of Chemical Engineering

Dane Wittrup
Koch Institute for Integrative Cancer Research at MIT

"This is a prediction of a mathematical model for tumor targeting, and maps out the effects of size and binding affinity on tumor uptake.   What is interesting is that larger drugs and smaller drugs accumulate to a much greater extent than intermediate-sized drugs."

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