The Elegance of Viruses and Their Broad Utility to be used as Molecular Substrates 1
The Elegance of Viruses and Their Broad Utility to be used as Molecular Substrates 1
Mohamad Najia, Anna Le, Paul Blainey
Koch Institute at MIT, Broad Institute, MIT Department of Biological Engineering
The goal of our research is to create a technology that allows for the measurement of a cell’s transcriptional state while keeping the cell alive. This image was some of the early evidence in the project that our viral machinery could be expressed within human cells and assemble into virus-like particles.
We think this image crystalizes the elegance of viruses and their broad utility to be used as molecular substrates to impart novel synthetic functions into mammalian cells.