Cellular Adhesion on a Microarray

Cellular Adhesion on a Microarray

Submitted by Nathan E. Reticker-Flynn of the Bhatia Lab at the Koch Institute

Koch Institute at MIT, Institute of Medical Engineering and Science, MIT Department of Biology

"Extracellular matrix (ECM) molecules are a family of molecules that fill the space around cells. During cancer progression, interactions between cells and their surrounding ECM are perturbed in a manner that permits invasion and metastasis. To understand this process better, we engineered a microarray technology that allows us to query interactions between cells and hundreds of unique combinations of ECM molecules. This image depicts cells adhered to a single island of one ECM combination."

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